Antonyms for the phrase "centers upon" could be words such as deviates from, disregards, ignores, or avoids. Other possibilities might include dismisses, overlooks, sidelines, or abandons. These antonyms all suggest a departure from a central focus or a lack of attention to a particular point or issue. They imply a lack of interest, importance, or relevance, or a failure to fully engage with a subject. In contrast, the phrase "centers upon" suggests a laser-like focus on a central theme or idea, implying depth, concentration, and intensity of thought or action. Overall, the chosen antonym will depend on the desired effect and the overall context of the sentence.