The phrase "drive up the wall" signifies an action or behavior that is aggravating and annoying to someone. The antonyms for this phrase are words that describe actions, behaviors, or situations that have the opposite effect, that is, they soothe, calm, and relax.
Some of the antonyms for "drive up the wall" include phrases like "put at ease," "calm down," "soothe," and "relax." Other words and phrases that convey the opposite meaning to "drive up the wall" are "pleased," "happy," "content," "tranquil," and "peaceful."
In short, if something is "driving you up the wall," you may need to seek out activities or situations that have the opposite effect and help you feel calm and at ease.