Histolysis is a term used in the field of biology to describe the process of breaking down or disintegrating of tissue. The term can also be defined as the dissolution or the destruction of cells or tissues. There are several synonyms that can be used to describe histolysis, including autolysis, necrosis, lysis, and atrophy. Autolysis is the process of self-digestion of cells or tissues by enzymes present within the cells. Necrosis is the death of body tissue due to injury or disease. Lysis refers to the breaking down of the cell membrane resulting in the release of cell contents. Atrophy is the shrinkage of a cell, tissue or organ due to disuse or lack of nourishment.