The opposite of low-spirited is high-spirited. High-spirited refers to someone who is full of energy, enthusiasm, and positivity. Other antonyms for low-spirited include optimistic, ebullient, vibrant, vivacious, euphoric, jubilant, and elated. These words describe someone who is full of life, radiates positive energy, and finds joy in every situation. Being high-spirited is essential for mental and emotional well-being. It helps to combat depression and anxiety, improves mood and self-esteem, and creates a positive environment around oneself. Hence, it is important to cultivate a high-spirited attitude towards life and strive for happiness and positivity in every situation.