The concept of being "most dirty-minded" implies a person who has an unrivaled focus on sexual or obscene subjects, so its antonyms would be words denoting someone who is clean, upright, or prudish in their thinking. Some potential antonyms include "innocent," "pure," "chaste," "virtuous," "decent," "wholesome," and "modest." These words describe individuals who steer clear of impure or indecent topics, choosing instead to focus on cleaner, more wholesome aspects of life. While the term "most dirty minded" has a negative connotation, these antonyms provide a positive outlook on individuals who embody more pure-minded values.