"Uptight" is an expression used to describe someone who is highly strung or anxious. Synonyms for this term include tense, anxious, nervous, edgy, agitated, jittery, and wound up. Other terms that can be used to describe someone who is "uptight" include worked up, keyed up, stressed out, on edge, apprehensive, fidgety, and uneasy. These synonyms reflect the range of emotions and feelings that someone who is "uptight" may experience. It is important to recognize that everyone experiences stress and anxiety differently, and what may be "uptight" for one person may not be for another.