The antonyms of the word "desolate" can range from "thriving" to "vibrant" or "joyful." Where "desolate" means a place that is bleak, empty or uninhabited, "thriving" denotes a place full of life or growth. Similarly, the opposite of "desolate" could be "populated" or "bustling" - words that paint a picture of a lively, active space. Additionally, "hopeful" or "happy" can also serve as antonyms to "desolate," indicating the presence of a positive, uplifting energy that is lacking in desolate spaces. By using these antonyms, we can better illustrate the stark contrast between a lifeless, desolate area and a bustling, thriving one.